Latest Articles
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Answers to Unsolved Rare Disease Mysteries May Be on the Horizon
In this opinion piece, Neil Ward explores how advances in sequencing could help to provide new insights for rare disease patients.
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What Are We Still Learning About Ancient Pathogens and Diseases?
Insight into the history of human–pathogen interactions, how different societies responded to disease and the origin of pathogens supports our understanding of human health and evolution. We explore what we're still learning about ancient pathogens and diseases.
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Your Gut Is Proof That You Lived Through a Pandemic
A microbiome analysis study highlights that pandemic-related lifestyle changes may be responsible for alterations seen in the microbial profile of the small intestine before versus during the COVID-19 pandemic.
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Feeding Tomorrow: Exploring the Next Frontier in Food
Our food system is at a pivotal moment; there is enormous potential for innovation to unlock more healthy, accessible and sustainable diets for all, but we are simultaneously facing huge global challenges.
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An Introduction to Bayesian Statistics
Bayesian statistics has emerged as a powerful methodology for making decisions from data in the applied sciences. Bayesian brings a new way of thinking to statistics, in how it deals with probability, uncertainty and drawing inferences from an analysis.
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Gene Therapy: A New Frontier in Disease-Modifying Therapies
The gene therapy landscape is dynamic and constantly shifting. In this article, we will review major advances in disease modification for illnesses that presently still lack effective treatments, as well as some challenges and approaches to overcome them.
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Implanting Microdevices Into Brain Tumors To Determine the Best Treatment
Scientists have demonstrated the potential for using intratumoral microdevices (IMDs) to test various cancer drugs on the tumor before implementing systemic treatment. The approach could offer a hope in tackling hard-to-treat gliomas.
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Orthogonal Validation: A Means To Strengthen Gene Editing and Gene Modulation Research
From RNAi to CRISPR, there are several methods that researchers can use to manipulate gene function. This article explores how orthogonal validation – the synergistic use of different methods – makes genetic perturbation studies more robust.
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An Introduction to Capillary Electrophoresis: Theory, Practice and Applications
Capillary electrophoresis is a powerful separation and analysis technique that offers quick and efficient results. In this article, we explore how it works, variations on the technique and their applications.
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The Potential for Groundbreaking Discoveries With CRISPR Screening
In this article, we consider various platforms to modulate gene expression and the potential of CRISPR-Cas systems to understand and treat diseases, from cancers and congenital disorders to overcoming the growing prevalence of antimicrobial resistance.
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