Resolving Brain Architecture With Comprehensive Spatial Gene Expression

Spatially resolved gene expression can provide a powerful complement to traditional histopathology methods, enabling a greater understanding of cellular heterogeneity and organization within the central nervous system. Integrated sequencing and histological data from the Visium Spatial Gene Expression assay can enable unbiased clustering of cell types that reliably correlates with the neuroanatomy of both rodent and human specimens. Plus, the addition of immunofluorescence enables a deeper, more complete assessment of brain architecture in a single experiment.

Download this data spotlight to learn more about:

• Characterization of discrete neuroanatomical brain regions
• Mapping expression of genes to specific brain regions or structures
• Visualizing spatial patterns of gene expression together with protein detection by immunofluorescence