Latest On-Demand Webinars & Online Events

As modalities of proteins continue to evolve and increase in complexity, peptide mapping remains a critical workflow in determining and monitoring post-translational modifications and other quality attributes.

Detailed and sensitive characterization of ionizable lipids that make up lipid nanoparticles (LNP) and their related impurities is necessary to ensure the quality of mRNA therapies. Additionally, there are mRNA quality attributes such as 5’ capping that directly impact efficacy and safety.

Speaking at the Vaccine Research & Development 2022, Kyle Luttgeharm, PhD, Product Manager from Agilent presented their talk on IVT RNA production and
accurate and precise mRNA analysis.

During this webinar, you will understand how capillary electrophoresis (CE) and LC-MS are being used to ensure vaccine and cell and gene therapy product quality. We will discuss how LC-MS is being used to identify impurities present in lipid nanoparticle (LNP) vaccines that have been found to deactivate mRNA. We will also cover how CE is being used in viral vector production to ensure product quality.

This Technology Networks event features exclusive talks focused on the most recent and innovative developments in the world of cell and gene therapies. Our expert speakers will highlight the opportunities cell and gene therapies provide for the treatment of disease and injury, including how cell therapies are providing novel solutions for rare diseases such as Duchenne muscular dystrophy.

This exclusive Technology Networks webinar focuses on the most recent and innovative strategies for therapeutic antibody development and production. Your speaker, Professor Brockwell, will describe the development and use of a new assay to investigate important proteins in disease screening and the biopharmaceutical industry.

Analyzing lipids can be a challenge but combining tandem mass spectra obtained from electron-activated dissociation (EAD) can make the process easier. In fact, over 1000 lipids can be analyzed by ballistic data-dependent acquisition liquid chromatography-mass spectrometry. This methodology produces a large number of high-quality EAD fragmented spectra, making annotation the limiting factor, but combinatorial fragmenters can be used to effectively solve this challenge.

In this webinar, we demonstrate how the ZenoTOF 7600 system can be used in a workflow for the routine analysis of lipids that enables the resolution of sn-isomerism and double bond positions from high-throughput EAD mass spectrometry data.

Map proteins, examine metabolic activity and dig deeper into cellular biology by adding spatial localization to your current methodologies. In this webinar, we’ll showcase this novel workflow, highlighting the benefits it can bring to your research.

The field of mass spectrometry has advanced tremendously over the last decade on both the hardware as well as the software side. Nevertheless, we still do not use the full capacity of the acquired proteomic data and several layers of information get lost in typical label-free quantification data-dependent acquisition proteomic datasets. A major source of this information loss is the presence of chimeric spectra, which contain fragment ions from multiple peptides, and the inability to fully interpret them.

In this webinar, we explore how the CHIMERYS intelligent search algorithm gives us a handle to elucidate the hidden traces within chimeric spectra. We’ll also discuss how CHIMERYS increases instrument efficiency and protein identification rates through deconvolution of chimeric spectra, enabling new data acquisition strategies with wide-window acquisition.

In this webinar, Dr. Catherine Houlihan, will describe an unrecognized case of viral hemorrhagic fever imported into the UK and the important lessons learned for the emergency clinicians, GPs, virologists, infection specialists and public health doctors.