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Cancer Genetics – News and Features

A scientist loading samples into a microwell plate.
Article

Advances in CHO Cell Line Development for Biotherapeutics

A diverse array of biological medicines are now used to prevent and treat a wide range of illnesses. This article will discuss the development of cell lines in biopharma and will touch on key considerations, such as future manufacturability.
Double helix structure of DNA.
News

“DNA Loops” in Pediatric Brain Tumors Double Relapse Risk

A study of newly created databases of medulloblastoma has found that patients with tumors containing circular extrachromosomal DNA are twice as likely to relapse and three times as likely to die within five years of diagnosis.
Artistic representation of the gene clusters that influence cancer progression.
News

4,749 Key Gene Clusters Influence the Progression of 32 Different Cancer Types

Researchers have released a groundbreaking study identifying 4,749 key gene clusters, termed “prognostic modules,” that significantly influence the progression of 32 different types of cancer.
A gold strand of DNA.
News

187 New Genetic Variants Linked to Prostate Cancer

The largest and most diverse investigation into prostate cancer genetics yet, which included major increases in representation among men from different racial and ethnic groups, has revealed 187 new risk variants.
Breast cancer cells, with the nucleus shown in blue and microfibers and stress fibers shown in red and green.
News

Vitamin B5 Levels Influence Tumor Growth in Mouse Model of Breast Cancer

New research has discovered that breast cancer cells expressing the Myc gene rely heavily on vitamin B5 to grow and survive, which could potentially be exploited as a therapeutic avenue.
A person wearing gloves draws liquid from a vial into a syringe with a needle.
News

Vaccinating Both Girls and Boys Against HPV Is Best To Prevent Cervical Cancer

Vaccinating both girls and boys against HPV is the best way to prevent cervical cancer, reports a new study. Gender-neutral vaccination induces herd immunity that will help to eradicate cancer-causing virus types.
A person holding a cigarette.
News

Tobacco Smoke Linked to Mutations That “Stop” Cancer-Fighting Proteins

A new study has revealed that tobacco smoke can cause specific DNA changes that can prevent anti-cancer proteins from being fully constructed, representing one way that tobacco smoking causes cancer.
Three in-focus cells with many more out of focus behind them.
News

Formaldehyde Disrupts Cellular Epigenetics

An international team of researchers has discovered that formaldehyde, a widely spread pollutant and common metabolite in our body, interferes in the epigenetic programming of the cell.
White pills on a blue background.
News

Mechanism Behind Aspirin’s Protective Effect Against Colorectal Cancer Identified

Aspirin has been shown to reduce colorectal cancer risk and inhibit cancer progression. A new study has revealed the molecular mechanisms behind these effects.
Cancer cells.
News

New Mechanism Uncovered in the First Oncogene, Over 40 Years Later

In the late 1970s, the relationship between the c-Src gene and cancer was discovered. Since then, c-Src has been found to be overactivated in half of colon, liver, lung, breast, prostate and pancreatic tumors, but its function is not yet understood.
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