Single-Cell Analysis – News and Features

A statistical model that removes background noise from single-cell transcriptomic data has been developed.

Mucosal-associated invariant T (MAIT) cells don't obey the usual immune cell rules, and new research has revealed another "superpower" of this cell type.

Chinese scientists report the first birth of a live chimeric monkey whose cells largely derive from a line of monkey stem cells. Their findings are published in Cell.

Precision treatment for rheumatoid arthritis is key. New research has used a cellular atlas to outline the variety of cellular causes, which may inform targeted, effective therapies.

Researchers at Karolinska Institutet, Sweden have uncovered the molecular logic underpinning the assembly of spinal circuits that control the speed of locomotion in adult zebrafish.

Researchers have shown that dengue virus can disrupt the immune system in children, leading to more severe disease. These results could lead to better diagnosis and treatment.

Organoids help researchers understand biological processes in health and in disease. It is, however, difficult to influence the way in which they organize themselves into complex tissues. Now a group has found a new way to do so.

Previously, touch was thought to be detected only by nerve endings present within the skin and surrounding hair follicles. New research has found that cells within hair follicles are also able to detect the sensation.

A recent discovery, published in PLoS Genetics, challenges the “rulebook” of DNA. We speak with the first author, Dr. Jamie McGowan, to learn about the accidental finding and what it means for synthetic biology.

Researchers have unpicked the mechanism behind how Kaposi's sarcoma herpesvirus reprograms immune cells, increasing inflammation and making an individual vulnerable to cancer development.