High-Throughput Screening – News and Features

A single master regulator of the genome can be used to reprogram a network of thousands of genes in T cells and greatly enhance cancer cell killing.

This article focuses on the use of high-throughput screening approaches in drug discovery and discusses the latest developments in this area.

Cornell researchers have harnessed the power of baker’s yeast to create a cost-effective and highly efficient approach for unraveling how plants synthesize medicinal compounds.

Biopharmaceuticals require careful analysis during research, development and manufacturing. In this article, we highlight some of the analytical techniques employed in biopharmaceutical analysis, and how the field is evolving to meet new challenges.

With a revolutionizing novel system that combines brain organoid technology and intricate genetics, researchers can now comprehensively test the effect of multiple mutations in parallel and at a single-cell level within human brain organoids.

In this article, we consider various platforms to modulate gene expression and the potential of CRISPR-Cas systems to understand and treat diseases, from cancers and congenital disorders to overcoming the growing prevalence of antimicrobial resistance.

In a landmark study of 125 Australian children with high-risk cancer, researchers have found that they can improve the chances of finding the right drug to kill their individual cancer through a new system of rapid drug screening.

Researchers have modulated a protein related to the immune system to slow the progress of amyotrophic lateral sclerosis (ALS) in mice.

Preliminary results of a study show that a novel, selective inhibitor of protein arginine methyltransferase 5 demonstrated antitumor activity in patients with advanced malignant solid tumors or B cell non-Hodgkin lymphomas.

Revvity announced its newly established Scientific Centre of Excellence in Cambridge, where scientists can outsource their research needs to Revvity experts. Technology Networks visited the site to learn more about how Revvity is supporting its customers in their drug discovery efforts.