Next-Generation Sequencing – Multimedia

Learn about single–tube workflow for simultaneous preparation of DNA and RNA libraries from single sample input and its advantages

In this infographic, we explore the milestones that led to the spatial transcriptomics techniques of today, beginning decades before the genomic revolution.

In this episode we discuss environmental monitoring, regulations, and introduce the Applied Biosystems MicroSEQ™ Rapid microbial ID system.

While magnetic beads provide a faster and easier solution than more complex, conventional methods, sometimes off-the-shelf solutions do not always offer the specificity or binding capacity required.

Biological and biomedical research used to be a field anchored down by the weight of time-consuming manual tasks. Involved and laborious wet-lab processes slowed output to a crawl.

But now, high-throughput technologies have ramped up the speed of science. In this infographic, we take a deep dive into how these technologies have changed the game.

Despite the valuable transcriptomic information provided by probe-based spatial assays, detecting immune cell infiltration can pose challenges

There is more to DNA than A, C, G and T, epigenetics plays a causal role in cell fate, aging and disease development. Genetic and methylation data together on the same read allow us to get a more complete picture of genome biology. Constrained to measuring four states of information, existing NGS- based technologies sacrifice genetic for methylation calling.

Liquid biopsy for profiling of cell free DNA (cfDNA) in blood holds huge promise to transform how we experience and manage cancer by early detection and identification of residual disease and subtype. However, a standard blood draw yields an average of only 10 ng of cfDNA, of which DNA derived from the tumor is a small minority.

Download this guide to explore tips on how to avoid issues during NGS experiment design, tissue/specimen handling and isolation of nucleic acids.

Formaldehyde fixed & paraffin-embedded (FFPE) tissue blocks are one of the most commonly used and archived sample types. However, some preservation approaches can result in the degradation of RNA and hinder transcriptome profiling .