Identifying Metabolites With Confidence
Understanding the effects of in vitro drug metabolism is a key aspect of drug discovery and development. However, researchers must be able to make confident decisions quickly and easily.
Electron-activated dissonance (EAD) is a novel orthogonal fragmentation technique that supports drug metabolism studies by providing more information-rich product ion spectra.
This application note presents a new workflow for in vivo metabolism studies that incorporates EAD and enables researchers to develop confident structure-metabolic stability relationships for pharmaceutical drugs.
Download this application note to discover how you can:
- Detect low-level metabolites with enhanced sensitivity
- Achieve faster characterization and identification of metabolites
- Streamline data acquisition and processing workflows