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Gene and Cell Therapy

This page provides educational resources, events, news and products related to gene and cell therapy. Content will cover aspects from the techniques and technologies used, to the increasing numbers of conditions being addressed by these therapies.

Gene and Cell Therapy – Highlights

Illustration of plasmid DNA being dispensed from a pipette tip onto a cell culture for transfection.

An Introduction to Transfection, Transfection Protocol and Applications

In this article, we discuss the fundamentals of transfection, provide an overview of some of the commonly employed methods and a sample protocol. Finally, we consider some of the key applications of transfection.

Gene Therapy: A New Frontier in Disease-Modifying Therapies

The gene therapy landscape is dynamic and constantly shifting. In this article, we will review major advances in disease modification for illnesses that presently still lack effective treatments, as well as some challenges and approaches to overcome them.

Advances in Gene Therapy

In this infographic, we explore the latest advances in gene therapy, including production and delivery mechanisms.

Next-Generation Analytical Solutions for Cell and Gene Therapy

In medicine, gene therapy is the process where nucleic acids are delivered to a patient’s cells as a therapeutic drug to treat an array of genetic diseases. All gene therapies utilize either viral or non-viral vectors to deliver the DNA or RNA into the host cell.

An Introduction to Electroporation – A Tool for Transfection and Competent Cell Generation

There are many reasons you may want to deliver something into a cell, be it genetic material or a therapeutic drug, and electroporation is a vital tool to achieve this. In this article, we will consider what electroporation is, how it works and how it’s used.

Gene and Cell Therapy – News and Features

Cancer Cell “Memories” May Lead to Improved Lung Cancer Treatments

Research shows that some lung cancer cells retain a “memory” of the healthy cell where they came from — one that might be exploited to make an emerging type of lung cancer treatment called KRAS inhibition more effective.

Novel Microfluidic Method Optimizes Stem Cell Extraction for Advanced Cell Therapies

Traditional bone marrow aspirate (BMA) stem cell extraction methods are complex, time-consuming, and yield poor results due to antiquated centrifugation techniques.

Inability of Macrophages To Penetrate Tumors Could Explain Cell Therapy Failures

Macrophages, a type of white blood cell that can destroy invading pathogens, have an innate ability to infiltrate tumor cells, making them a potentially important tool in treatments that use transplanted cells to fight disease, known as cell therapy.

Disrupting One Gene in CAR T Cells Makes Them More Potent

Disrupting one gene in CAR T cells used for cancer therapy makes them more potent and able to fight the cancer for longer, reports a new study.

Industry Insight

Why the Time Is Now for Allogeneic Cell Therapies

Andrew Schulman explores why we need allogeneic therapies, the importance of collaboration to keep the momentum, and challenges and predictions for the future.

Genome’s “Master” Regulator Could Be Used To Enhance T-Cell Therapy

A single master regulator of the genome can be used to reprogram a network of thousands of genes in T cells and greatly enhance cancer cell killing.

Gene and Cell Therapy – Multimedia

A test tube containing pink liquid is held up by a gloved hand in front of a DNA model.

Cell and Gene Therapies: From the Lab to the Clinic

DNA double helix.

Economies of Scale: The Top 5 Considerations for Successful Cell and Gene Therapy Fill/Finish Scale-Up

mAbs3 mycoplasma 3rd party lp ebook

Ensuring Biotherapeutic Products Are Mycoplasma-Free

Gene and Cell Therapy – Webinars and Online Events

Thermo FIsher Scientific and BioAgilytix

Securing Cell Therapy Success: The Role of PCR in Quality Control

bionano

Optical Genome Mapping: Transforming Cell and Gene Therapy

mRNA

Optimizing mRNA Purification Conditions by Using a High-Throughput Screening Approach

Related Products

iPSCs To Accelerate Gene and Cell Product Development

iPSCs To Accelerate Cell and Gene Product Development

Cytiva and RoosterBio Collaborate To Address Exosome Manufacturing Challenges

Broken String Biosciences’ Induce-Seq Platform Demonstrates Impact of Structural DNA Changes on Specificity of CRISPR-Cas9 Gene Editing

Integrated DNA Technologies Opens New Therapeutic Manufacturing Facility

New Mid-Term Guidance 2024 – 2028 Supported by Ramp-Up of Growth Projects

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