Driving Genome-Wide Consistency in Cellular Reprogramming
Biological variance poses challenges when using human iPSC-derived cells in vitro, leading to inconsistent experimental results and data variability.
In this webinar, Dr. Ania Wilczynska will discuss a new method for making human iPSC-derived cells, opti-oxTM precision cellular reprogramming technology. This technology synchronously reprograms iPSCs with remarkable genome-wide consistency. Through transcriptome analysis, Ania will demonstrate that opti-ox reprogrammed iPSC-derived cells show minimal biological variance between users, manufacturing lots and time periods.
You’ll discover how this long-term cellular consistency can enable researchers to investigate functions of genes or responses to various compounds in great detail, using a human-relevant model system.
- Understand the factors impacting experimental variance when using iPSC-derived cells
- Explore a new method of cell generation called opti-ox, which enables precise reprogramming of iPSCs into defined, functional cell types
- Discover the impact of opti-ox technology on cell consistency
- Hear how this technology has been used for consistent and precise reprogramming of iPSCs to glutamatergic neurons, GABAergic neurons, microglia and sensory neurons
