Latest App Notes & Case Studies
App Note / Case Study
Easy Set-Up for Protein Crystallization Experiments
This app note highlights how a handheld electronic pipette can help researchers save time and increase homogeneous crystal growth.
App Note / Case Study
Real-Time Quality Control Software for Metabolic Phenotyping
QC can be performed after data acquisition, but unexpected deviations can waste valuable time and resources. Instead, real-time QC allows for active monitoring of data quality as the analysis is being performed, preventing errors that can compromise the analysis.
App Note / Case Study
Oligonucleotide Purity Analysis With Side-Product Identification and Quantitation
Oligonucleotides play a crucial role in modern drug development, therefore their accurate characterization is essential. However, given the sheer complexity and diversity of the types of oligonucleotides that are in clinical development, a range of diverse analytical approaches are necessary.
App Note / Case Study
Protein Sequence Analysis: Next-Generation vs Mass Spectrometry Methods
Mass spectrometry is regarded as the gold standard for protein identification; however, this technique cannot easily discriminate between protein variants and is not accessible to everyday scientists due to the high cost, space and expertise required.
App Note / Case Study
Accelerate Discovery with SWATH DIA Mass Spectrometry
This application focus presents the exciting technology behind advances in DIA and discusses how it can be used to enhance research.
App Note / Case Study
Enhance Your Annotation Confidence in LC-TIMS-HRMS-Based Bile Acid Profiling
Bile acids are well known for their roles in cholesterol homeostasis, lipid absorption and as metabolic signaling molecules. They are implicated in a variety of disease states and therefore serve as an exciting focus on research in novel biomarker discovery.
App Note / Case Study
Cultivating Stem Cells: A Guide to Choosing the Right Culture Medium
Pluripotent stem cells are the gateway to creating cells for disease modeling, regeneration and drug discovery. When it comes to growing such infinite potential, selecting the right culture medium is key!
App Note / Case Study
New Standards for Plasma Proteomics
Identifying novel biomarkers with bottom-up proteomics remains a substantial challenge due to the wide concentration ranges and potentially low abundance of important analytes.
App Note / Case Study
Multiplex and Multiomic Imaging of Targeted Proteins and Small Molecules
Need a routine analytical technique that can provide protein expression profiling and targeted drug imaging? MALDI Imaging is used to determine the spatial distribution of molecules in a tissue section, for more complete multiomic information.
App Note / Case Study
Rapid 4D Analysis of Lipid Nanoparticle Components
Lipid nanoparticles (LNPs) have emerged as effective delivery vehicles for mRNA vaccines and nucleic acid-based drugs. Hence, the analysis of their composition, stability, and biological interactions is essential in drug development and delivery.
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