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Advanced Cell Models

This page provides educational resources, events, news and products related to advanced cell models. Content will cover aspects from the creation of organoids and organs-on-chips, to how they are applied to solve research questions, discover and test therapeutics and improve health.

Advanced Cell Models – Highlights

Microphysiological Systems content piece image

Microphysiological Systems

Microphysiological systems (MPS) are two- or three-dimensional cellular platforms that are designed to recapitulate the physiology and function of the human body in vitro.

Cellular Insights: How Researchers Are Using Cell Models To Study the Mechanisms of Disease

This article will discuss how cell models are enabling researchers to elucidate the underlying biological mechanisms of disease to support diagnostic and therapeutic development.

How Far Can Organs-on-Chips Go On Their Own?

Great hope has been placed on organ-on-chip models to provide a complex and predictive in vitro models that can recapitulate the human drug response. How far can they go? This article delves into whether organ-on-chips can live up to expectations, and in particular, whether they can do it alone.

Advances in Spheroid and Organoid Engineering and Applications

In this article, we look at some recent advances and applications and where the field of three-dimensional tissue culture is heading.

An Introduction to Organoids, Organoid Creation, Culture and Applications

Organoids have revolutionized biological and medical research and proven to be excellent substitutes for animal models in preclinical studies. Here, we discuss what organoids are and how they have been developed over the years to become popular research tools.

Advanced Cell Models – News and Features

Researchers Grow Mini Colons With Immune Components

A team has developed a sophisticated model for studying the diseased colon that could lead to the development of personalized treatments for colon-related diseases, such as cancer and inflammatory bowel disease (IBD).

Uncontrolled Growth Is an Advantage and Weakness for Cancer Cells

ETH Zurich researchers are illuminating what can happen when cells exceed their normal size and become senescent. Their new findings could help to optimise cancer treatments.

Extracting Meaningful Data With High-Throughput Drug Discovery Approaches

This article focuses on the use of high-throughput screening approaches in drug discovery and discusses the latest developments in this area.

Intestinal Organoids Shed Light on Causes of Cronkhite-Canada Syndrome

Human intestinal organoids have shed new light on the potential causes of Cronkhite-Canada syndrome, a rare condition characterized by abundant non-cancerous growths or polyps in the intestine.

Researchers Use Light To Regulate Gene Expression in Organoids

Organoids help researchers understand biological processes in health and in disease. It is, however, difficult to influence the way in which they organize themselves into complex tissues. Now a group has found a new way to do so.

Human Organoids Aid Identification of Key Regulator in Cell Differentiation

Researchers used gut organoids to perform a systematic CRISPR screening of 1800 human transcription factors and identified ZNF800 as a key regulator of the differentiation of a specific gut cell type, the enteroendocrine cells.

Advanced Cell Models – Multimedia

Upscaling Organoid Research for Sharper Biological Insights

Upscaling Organoid Research for Sharper Biological Insights

organ on a chip

An Introduction to Organ-on-a-Chip Technology

Istock

Working with Corning Matrigel Matrix: Tips, Tricks and Expert Advice

Advanced Cell Models – Webinars and Online Events

Methods and Reagents for Culturing and Characterizing Organoids and Cancer Spheroids

Methods and Reagents for Culturing and Characterizing Organoids and Cancer Spheroids

AMA:Body-On-A-Chip Promotional Image

Ask Me Anything: Body-on-a-Chip

How To Stain and Clear Large Samples for 3D Light Sheet Microscopy content piece image

How To Stain and Clear Large Samples for 3D Light Sheet Microscopy

Related Products

Cultrex™ BME Matrices

Cultrex™ BME Matrices: Mimic Your Cells Native Microenvironment

CellXpress.ai Automated Cell Culture System - The Future of Cell Culture Backed by Machine Learning and Data-Driven Science

App Note / Case Study

Novel Organoid Platform for High-Throughput Drug Discovery

CellCelector Flex - Single Cell, Colony or Organoid Selection and Retrieval

InSphero Signed Distribution Agreement To Facilitate Purchasing 3D In Vitro Products Within the European Union

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