Latest Articles

In this op-ed article, Michael Kinch explains his optimism around ChatGPT which, in his words, centers around the possibility that we as a society might start to question "claims" and "truths" that we encounter daily.

A revolutionary gene therapy has become a transformative treatment for children with metachromatic leukodystrophy (MLD). But substantial barriers to access for this groundbreaking therapy remain.

In this article, we discuss the fundamentals of transfection, provide an overview of some of the commonly employed methods and a sample protocol. Finally, we consider some of the key applications of transfection.

The Nobel Prize winning CRISPR-Cas genome editing technology is being adopted for a wide variety of research applications. In this article, we will explore what these applications are and outline the progress of CRISPR methodologies in recent years, in addition to current bottlenecks in CRISPR research and how we can look to address them.

The 11th-hour passage of The FDA Modernization Act gave a much-needed boost to the advocates of new alternative methods (NAMs) for preclinical testing. In this article, we take a look at why NAMs are needed and what the new legislation means for pharmaceutical companies.

Regulators are increasingly collaborating on a global scale, sharing expertise across regions for mutual benefit. In this article, Piety Rocha examines this upward trend.

This article explores new workflows using data-driven modeling to improve culture medium and new control algorithms allowing for better modulation within the bioprocess design space.

In this opinion piece, Han Wei and Brittany Niccum outline the need for vigilance about what’s happening in the natural world and how collaboration can help to identify and prepare for the next significant zoonotic threat.

Structural biology uses a variety of techniques to determine the 3D structures of biomolecules such as proteins, nucleic acids and their complexes. In this article, we consider the key techniques, their role in structural biology, strengths and limitations.

Variation is a powerful force in biology. This article explores the importance of moving away from one-size-fits-all approaches and towards diversifying cell lines and clinical trials.