News

Ohio State scientists are exploring how common synthetic hormones used for birth control affect the prefrontal cortex, an area of the brain that continues to develop throughout adolescence.

A small molecule drug, one of 27 million screened in a library of potential new drugs, has shown promise as a painkiller, outperforming gabapentin for treating four types of chronic pain.

Researchers suggest that when used in a form that can be delivered directly into the tumor cell, polyinosine–polycytidylic acid (pIC) suppresses tumor growth, induces cancer cell death and enhances survival.

A phase 1 trial for Lepodisiran has shown it can reduce levels of lipoprotein A, a key driver of heart disease risk, by 94%, with results lasting for nearly a year.

Researchers have described a previously unknown step in the complex process by which dietary cholesterol is processed in the intestines before being released into the bloodstream – potentially revealing a new pathway to target.

Looking around us, we can see that people age at different rates. But what about inside? Do all cells age in the same way? Researchers have now shown in the liver of mice that liver cells age differently depending on where they are located.

A review of 15 years’ worth of data from the Vitamin D Antenatal Asthma Reduction Trial (VDAART) found that vitamin D supplementation during pregnancy reduced rates of asthma and wheezing in children compared to standard prenatal multivitamin.

An international team of researchers has demonstrated that genetically engineered yeast cells can produce the natural plant product alstonine, which has shown positive effects in treating schizophrenia.

An international group of 35 scientists, including IRES’s Gunilla Öberg, is calling out conflicts of interest plaguing global plastic treaty negotiations and that have interfered with timely action on other health and environmental issues.

The largest and most diverse investigation into prostate cancer genetics yet, which included major increases in representation among men from different racial and ethnic groups, has revealed 187 new risk variants.