Latest App Notes & Case Studies

Custom oligo synthesis can result in the formation of impurities. Hence, final products must be characterized to ensure they meet quality assurance and control standards.

LC/MS methods can be used to analyze a wide range of oligo samples. However, ion-pairing reagents can interfere with analyses and present challenges in multi-use systems.

This application note demonstrates how Single Cell Immune Profiling and Barcode Enabled Antigen Mapping (BEAM) can be used to profile thousands of hPBMCs from a single donor.

CAR-T cell therapy has emerged as one of the most promising novel treatments in the fight against cancer.

Laboratory Information Management Systems (LIMS) is becoming increasingly important in GMP regulated environments in order to ensure data integrity and faster working practices.

Outsourcing quality management activities can save biomanufacturers time, money and resources. It can support scientists in bringing life-changing therapeutics to market swiftly and efficiently.

Both RUO and cGMP compliance play important roles in the drug discovery pipeline. However, meeting regulatory demands can be a challenge when accelerating new drugs to the clinic.

Discover an automated processing workflow that utilizes both EAD and CID data for the most confident characterization of pharmaceutical drug metabolites.

Metabolism is a key driver of CAR-T cell fitness and function. Hence, metabolic preconditioning methods can enhance the bioenergetic capacity of CAR-T cells in culture, supporting their persistence and antitumor activity

Protein-targeting chimeras (PROTACs) have gained significant attention recently due to their high potency in nanomolar drug concentrations and target selectivity. However, low test concentrations in complex matrices present analytical challenges.