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A scientist holding a glass vial with a DNA model in the background.
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Parkinson’s Disease Gene Therapy Shows Promise in Animal Studies

Researchers have developed a gene therapy strategy to selectively manipulate Parkinson's disease-affected circuitry and attenuate the core motor symptoms of Parkinson's disease in rodent and nonhuman primate animals.
The structure of an antibody, with different sections labelled in red, orange, yellow and white.
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Antibody Targets Tumor-Promoting Molecules Deep Within Cancer Cells

A new approach to cancer treatment uses IgA antibodies to target and destroy tumor-promoting molecules deep within cells and has been described as a more precise, long-lasting and less toxic approach.
Human heart cells grafted into a nonhuman primate heart aside native heart cells.
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Combining Cell Types Could Lead to Improved Cardiac Cell Therapy

A new study points to an improved method for regenerating heart muscle following a heart attack. Researchers have harnessed a combination of lab-grown cells to regenerate damaged heart muscle.
Computer-generated image of "AI" on a computer chip.
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AI Identifies Potential Gonorrhea Vaccine Targets

Researchers have used artificial intelligence (AI) to identify promising target proteins with the potential for development into a vaccine against gonorrhea.
The RD-43 Antibody under fluorescent lighting.
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Novel Antibody Can Stop the Spread of Breast Cancer

An enzyme that may help some breast cancers spread can be stopped with an antibody created in Cold Spring Harbor Laboratory. With further development, the antibody might offer an effective drug treatment for those same breast cancers.
Stem cells.
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Novel Gene Therapy for Hunter Syndrome

The UK regulatory authorities have approved the first ever trial of a revolutionary gene therapy for young children diagnosed with Hunter syndrome, a devastating rare lysosomal storage disorder.
T cells.
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T-Cell Discovery Has Potential for Engineering Custom Immune Responses

Researchers made the breakthrough discovery that the genetically encoded T-cell receptor (TCR) sequence that humans develop in early childhood determines a T cell’s function.
A person jogging in a park.
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25 Minutes of Physical Activity May Offset Risk of Death From Prolonged Sitting

Just 20–25 minutes of moderate to vigorous physical activity each day may be enough to combat a highly sedentary lifestyle's increased risk of death, suggests a new study in the British Journal of Sports Medicine.
Vials with different colored caps arranged in rows.
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Minifridge-Sized Reactor Quickly Produces T Cells for Cancer Treatment

A new reactor the size of a minifridge that rapidly grows cancer-killing white blood cells could advance the availability of immunotherapy.
Protein structure.
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Harnessing the Innate Power of a Cell To Remove Problem Proteins

Stanford researchers who previously pioneered a new kind of protein degradation have mapped out how the process works, which could lead to new drug therapies for diseases like Alzheimer’s and cancer, and for rare childhood enzyme disorders.
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