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Latest App Notes & Case Studies

An Integrated Multiomic Approach for the Diagnosis of Metabolic Diseases content piece image
App Note / Case Study

An Integrated Multiomic Approach for the Diagnosis of Metabolic Diseases

Inherited metabolic disorders (IMDs) are a vast and complex group of rare genetic diseases presenting throughout a patient’s life span.
A Fully Integrated Spatial Biology Analysis Solution content piece image
App Note / Case Study

A Fully Integrated Spatial Biology Analysis Solution

Extracting biological insights from spatial data is vital to advancing science, however, the analysis of spatial multiomics data is only possible with a robust and scalable informatics solution.
Distinguishing Oxidative Impurities From Ionizable Lipids Used in LNP Formulations content piece image
App Note / Case Study

Distinguishing Oxidative Impurities From Ionizable Lipids Used in LNP Formulations

Lipid nanoparticles (LNPs), comprised of ionizable lipids, are used to deliver oligonucleotides to work as therapeutics or to stimulate the immune system, as in the initial mRNA-based COVID vaccines.
Characterization and Relative Quantification of mRNA 5’-Capping content piece image
App Note / Case Study

Characterization and Relative Quantification of mRNA 5’-Capping

Products based on mRNA have broad potential for use as therapeutics, and because mRNA leverages the translational machinery of the host cells, there is a significantly reduced risk of unwanted post-translational modifications.
Consistency is Key to Further Drug Discovery Research content piece image
App Note / Case Study

Consistency is Key to Further Drug Discovery Research

Energy metabolism plays a central role in a wide variety of cellular and physiological processes. Therefore, a deep understanding of how disruption to energy metabolism impacts cells can help in therapeutic drug discovery and development.
Going Library-Free for Protein Identification content piece image
App Note / Case Study

Going Library-Free for Protein Identification

Download this app note to discover a SWATH DIA workflow that:
Has the speed and sensitivity to acquire high-quality, high-resolution MS/MS data
Reduces the need to generate experimental libraries
Was used to identify 2-fold more proteins than a DDA workflow
Ensuring Quality Control of IVT RNA Workflows content piece image
App Note / Case Study

Ensuring Quality Control of IVT RNA Workflows

This tech note highlights technology that switches easily between DNA and RNA analysis to ensure quick and reliable quality checks and precise sizing of DNA and IVT RNA products.
High Resolution Mapping of the Breast Cancer Tumor Microenvironment content piece image
App Note / Case Study

High Resolution Mapping of the Breast Cancer Tumor Microenvironment

Single cell and spatial technologies that profile gene expression across whole tissues are revolutionizing the resolution of molecular states in clinical tissue samples.
Fast and Accurate Protein Quantitation content piece image
App Note / Case Study

Fast and Accurate Protein Quantitation

Protein quantitation is an integral part of many protein biology workflows and a necessary step before commonly used techniques such as protein electrophoresis, western blotting, mass spectrometry and immunoassays.
Analyzing Complex Spatial Data for Deep Insights content piece image
App Note / Case Study

Analyzing Complex Spatial Data for Deep Insights

The MACSima™ Imaging Platform is based on a highly multiplexed spatial proteomic technology providing a tremendous amount of complex data. MACS® iQ View – the integrated, easy-to-use analysis software – allows users to evaluate the spatial relationships of expressed markers and gain deep insights.
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