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Genomic "Tug of War" Could Influence How Cancer Patients Respond to Decitabine

A genomic tug of war for a gene activator could explain why some cancers respond to decitabine and others don't respond or become resistant over time.
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Hormone Therapy May Be Potential Treatment for Liver Fibrosis

Researchers have discovered previously unknown changes in a specific type of liver cells, potentially opening avenues for a new treatment for liver fibrosis, a potentially life-threatening condition.
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Parkinson's Disease Halted in Mouse Model

Researchers have shed new light on the cellular processes behind Parkinson's and illustrated how disease progression can be halted in a mouse model.
3D reconstruction of a TARP.
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Biologic “Patch” Activated by Natural Motion Could Help Fix Herniated Discs

The tension-activated repair patch used in animal trials plugs holes in discs in the spine like car tire patches and could prevent further disease progression.
Blue and red fluorescence microscopy of pancreatic cancer cells.
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Experimental Drug Obstructs Tumor Migration in Pancreatic Cancer

Researchers have identified the genetic changes that occur during pancreatic cancer metastasis and have found a drug to disrupt the process.
A girl sleeping.
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The Unknown Risks of Melatonin Use in Children

Nearly one in five school-aged children and preteens now take melatonin for sleep, and some parents routinely give the hormone to preschoolers, according to new research.
A photo of the needle that softens with body temperature, including a close up of the tip.
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An Intravenous Needle That Softens in the Body on Insertion

Researchers have developed an intravenous needle that softens and flexes when in the body, reducing the risk of damage to the blood vessel as patients receive medication.
Venus and Mars symbol drawn on eggs.
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Men Die 6 Years Before Women in the US

We’ve known for more than a century that women outlive men. But new research shows that, at least in the United States, the gap has been widening for more than a decade.
A strand of DNA shown in blue.
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Disrupting One Gene in CAR T Cells Makes Them More Potent

Disrupting one gene in CAR T cells used for cancer therapy makes them more potent and able to fight the cancer for longer, reports a new study.
A section of a model of a human spine.
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Existing Drug That Targets Sleeping Cells Could Be the Answer To Lower Back Pain

A study of senescent (inactive) osteoclasts in the vertebral column of mice suggests that using anti-senescent drugs could relieve the spinal sensitivity that causes lower back pain.
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