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A side-by-side comparison of cells supported by the oxygenation device (left) and cells without the device support (right).
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A Breath of Fresh Air Is Key for Cell-Based Therapies

In 2021, a University-led research team received a contract worth up to $33 million to develop an implantable “living pharmacy” to control the human body’s sleep/wake cycles. Now, the researchers have completed a major step toward achieving this.
Purple-gloved hands hold a cell culture dish.
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Powerful Immune Cells Engineered for Potential “Off-the-Shelf” Cancer Therapy

Scientists have developed a new method to engineer more powerful immune cells that can potentially be used for “off-the-shelf” cell therapy to treat challenging cancers.
A person wearing gloves draws liquid from a vial into a syringe with a needle.
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Vaccinating Both Girls and Boys Against HPV Is Best To Prevent Cervical Cancer

Vaccinating both girls and boys against HPV is the best way to prevent cervical cancer, reports a new study. Gender-neutral vaccination induces herd immunity that will help to eradicate cancer-causing virus types.
A synthetic strain of yeast.
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Half-Synthetic Yeast Engineered for the First Time

The Synthetic Yeast Genome Project 2.0 declares a major milestone: it has created a yeast strain comprising over 50% synthetic DNA.
Red media in a 12 well plate.
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New Method Improves Pancreatic Stem Cell Production for Potential Transplants

A University of Alberta team has developed a new step to improve the process for creating insulin-producing pancreatic cells from a patient’s own stem cells, bringing the prospect of injection-free treatment closer for people with diabetes.
Blue influenza virions surrounded by a green membrane.
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Studying the Evolutionary History of Flu Viruses Shapes Vaccine Development

Studying the evolutionary history of influenza viruses to quantitatively analyze how they evolved may help predict future strains and guide vaccine development.
Cancer cells.
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Modified CAR T-Cell Therapy Shows Improved Efficacy in Preclinical Study

Researchers at the University of Freiburg have now been able to prevent the exhaustion caused by CAR-T cell therapy and thus significantly improve the effect of the therapy in a preclinical animal model.
A plastic model of a heart.
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MicroRNA Could Create Starting Point for New Atherosclerosis Therapy

A specific microRNA molecule has been identified as a promising starting point for the investigation of new therapies for atherosclerosis.
A 3D rendering of a brain on a purple background.
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Reprogrammed Cells Could Tackle Autoimmune Brain Condition

A novel treatment based on CAR-T cells could help tackle encephalitis, a common autoimmune disease, by targeting and eliminating disease-causing cells.
The intimate contacts formed between dendritic cells (green) and T lymphocytes (blue and pink).
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Dendritic Cell Discovery Holds Key for Developing Novel Vaccines

The finding has major implications for the generation of a strong CD8 T lymphocyte response, a crucial factor in the effectiveness of vaccines against infection.
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