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Human microglia implanted in the hippocampus region of the brain of a mouse.
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Mutant Immune Cells in the Brain Heighten Alzheimer's Risk

A new MIT study finds that microglia with mutant TREM2 protein reduce brain circuit connections, promote inflammation and contribute to Alzheimer’s pathology in other ways.
A plastic model of a brain and a brain cell.
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Gene Expression Link to Suicide Explored

Suicidal behavior is driven by a mix of psychological, social and biological factors. New research has identified overactive inflammation and loss of critical protection mechanisms in the brain as potential contributors to suicide risk.
A model of a human brain with coloured string emitting from the sides.
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Humans Share the Blueprint of Their Brain With Sea Anemones

New research finds the same genetic mechanisms at work during neural development in both humans and Nematostella vectensis.
A brown bear.
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Grizzly Bears' Circadian Clocks Keep Going Through Hibernation

The internal clocks of grizzly bears appear to keep ticking through hibernation, according to a genetic study. This persistence highlights the strong role of circadian rhythms in the metabolism of many organisms including humans.
A neuron, connected to others.
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Parkinson's Disease Halted in Mouse Model

Researchers have shed new light on the cellular processes behind Parkinson's and illustrated how disease progression can be halted in a mouse model.
3D reconstruction of a TARP.
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Biologic “Patch” Activated by Natural Motion Could Help Fix Herniated Discs

The tension-activated repair patch used in animal trials plugs holes in discs in the spine like car tire patches and could prevent further disease progression.
A plastic model of the human brain, bisected to show the internal structures.
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Smaller Hippocampus Linked to Cognitive Decline

Shrinkage in the hippocampus area of the brain is associated with cognitive decline, even in people who don’t have amyloid plaques in the brain, reports new research.
A scientist in a lab.
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Improved Research Models for Parkinson’s Disease Created

Researchers developed an improved method to study Parkinson’s disease in the lab. Along the way, researchers also uncovered clues that may help scientists figure out how to detect Parkinson’s earlier and point the way toward better treatments.
People running.
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Daily Scheduled Exercise Helps To Sync Body Clock

Physical activities in the morning, associated with daily patterns of sleep/wake cycle, convey timing information from the light-sensitive central clock in the brain to the weight-bearing skeletal tissues.
A girl sleeping.
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The Unknown Risks of Melatonin Use in Children

Nearly one in five school-aged children and preteens now take melatonin for sleep, and some parents routinely give the hormone to preschoolers, according to new research.
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